Autoantibodies Against the Fibrinolytic Receptor, Annexin A2, in Cerebral Venous Thrombosis
نویسندگان
چکیده
منابع مشابه
Autoantibodies against the fibrinolytic receptor, annexin A2, in cerebral venous thrombosis.
BACKGROUND AND PURPOSE Cerebral venous thrombosis (CVT) may be a manifestation of underlying autoimmune disease. Antibodies against annexin A2 (anti-A2Ab) coincide with antiphospholipid syndrome, in which antiphospholipid antibodies (aPLA) are associated with thrombosis in any vascular bed. Annexin A2, a profibrinolytic receptor and binding site for β2-glycoprotein-I, the main target for aPLA, ...
متن کاملAutoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome.
The association of thrombosis and gestational morbidity with antiphospholipid antibodies is termed antiphospholipid syndrome (APS). Annexin 2 (A2) is a profibrinolytic endothelial cell surface receptor that binds plasminogen, its tissue activator (tPA), and beta(2)-glycoprotein I (beta2GPI), the main antigen for antiphospholipid antibodies. Here, we evaluate A2 as a target antigen in APS. Serum...
متن کاملSudden Bilateral Sensorineural Hearing Loss Secondary to Cerebral Venous Thrombosis
Introduction: Sudden sensorineural hearing loss (SSNHL) is an important otological emergency. Up to 90% of the cases are idiopathic. Cerebral venous thrombosis (CVT) is an extremely rare identifiable cause as it only represents 0.5% of all strokes. Case Report: In this paper, an unusual case of bilateral SSNHL secondary to bilateral CVT with rapid and complete recovery is reported. The patie...
متن کاملCerebral Venous-Sinus Thrombosis: A Case Series Analysis
Background: Cerebral venous-sinus thrombosis is an uncommon form but important cause of stroke, especially in young-aged women. Methods: We performed a retrospective descriptive-analytical study in which 124 patients with cerebral venous-sinus thrombosis, who referred to Nemazee Hospital, Shiraz University of Medical Sciences from January 2000 to March 2008, were included, and their dem...
متن کاملFibrinolytic therapy and deep venous thrombosis.
SIR,-Further to the interesting leading article "Nutrition and Sleep" (20 May, p. 418) one may ask whether sleep is not the "natural" state and wakefulness merely a res,pite for the satisfaction of instinctual (and socially inculcated) drives. The hibernating animal is unlikely to chance upon dangerous predators. On this model the satisfqction of drives would lead to sleep and their continued f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Stroke
سال: 2011
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.110.592121